1 00:00:00,000 --> 00:00:52,480 I 2 00:00:59,120 --> 00:00:56,540 okay we're with you Franklin hello 3 00:01:02,810 --> 00:00:59,130 welcome to the space shuttle Columbia on 4 00:01:05,000 --> 00:01:02,820 this mission fts 75 we have spent the 5 00:01:07,700 --> 00:01:05,010 last several days conducting research in 6 00:01:09,620 --> 00:01:07,710 microgravity science one particular 7 00:01:11,900 --> 00:01:09,630 experiment which I wanted to mention to 8 00:01:14,440 --> 00:01:11,910 you distant world involved in the 9 00:01:18,469 --> 00:01:14,450 crystallization of proteins in 10 00:01:20,330 --> 00:01:18,479 weightlessness in the proteins are some 11 00:01:24,680 --> 00:01:20,340 of the most fundamental building blocks 12 00:01:27,710 --> 00:01:24,690 for lives on our planet Earth they also 13 00:01:31,249 --> 00:01:27,720 play a key role in the life cycle of 14 00:01:33,440 --> 00:01:31,259 disease they control for example 15 00:01:38,330 --> 00:01:33,450 critical functions like reproduction 16 00:01:41,690 --> 00:01:38,340 like growth and of course that now with 17 00:01:44,960 --> 00:01:41,700 this in mind and in their continuous war 18 00:01:48,200 --> 00:01:44,970 against these modern medicine and 19 00:01:51,280 --> 00:01:48,210 pharmacology have focused more on the 20 00:01:55,280 --> 00:01:51,290 microscopic than the macroscopic world 21 00:01:58,430 --> 00:01:55,290 it is in fact in this rearm that we can 22 00:02:03,380 --> 00:01:58,440 better understand and hence defeat the 23 00:02:05,870 --> 00:02:03,390 enemy in fact the more precisely we know 24 00:02:09,650 --> 00:02:05,880 the protein structure of of a disease or 25 00:02:11,750 --> 00:02:09,660 a parasite the more effectively the 26 00:02:18,500 --> 00:02:11,760 weekend engineer drugs and medications 27 00:02:21,020 --> 00:02:18,510 or vaccines to counteract them if we 28 00:02:24,470 --> 00:02:21,030 were able to transport ourselves to the 29 00:02:27,800 --> 00:02:24,480 microscopic world we would find that 30 00:02:36,890 --> 00:02:27,810 this proteins look very much like this 31 00:02:36,900 --> 00:02:43,179 who are in fact three-dimensional 32 00:02:51,080 --> 00:02:46,780 arranged in very specific patterns 33 00:02:53,899 --> 00:02:51,090 booking structures present very specific 34 00:02:57,140 --> 00:02:53,909 notes and crannies to which other 35 00:03:00,649 --> 00:02:57,150 proteins bind and relate to their 36 00:03:04,250 --> 00:03:00,659 surroundings these lands are binding 37 00:03:05,839 --> 00:03:04,260 sides hold the key to many of the 38 00:03:09,289 --> 00:03:05,849 critical functions of the living 39 00:03:14,030 --> 00:03:09,299 organisms inhibiting some of the sides 40 00:03:16,940 --> 00:03:14,040 can alter can arrest can neutralize or 41 00:05:51,740 --> 00:03:16,950 in fact in the case of a disease can 42 00:05:51,750 --> 00:05:55,399 hello folks 43 00:07:56,020 --> 00:05:57,619 Oh Jeff hi Claude we're looking in the 44 00:07:56,030 --> 00:08:02,830 columbia were handed over to Goldstone a 45 00:08:15,110 --> 00:08:06,920 lot of the same columbia through 46 00:08:18,610 --> 00:08:15,120 gallstones okay and i got the big 47 00:08:24,440 --> 00:08:18,620 picture from rich when you ready to copy 48 00:08:29,000 --> 00:08:24,450 okay stories i have a picnic okay we 49 00:08:32,680 --> 00:08:29,010 will bring up edwards for tomorrow we 50 00:08:39,230 --> 00:08:32,690 will not attempt the first rev at KSC 51 00:08:42,140 --> 00:08:39,240 that's on orbit 234 we will take aim at 52 00:08:47,540 --> 00:08:42,150 the second opportunity at KSC which is 53 00:08:52,880 --> 00:08:47,550 235 if we waive off on that one we will 54 00:08:58,730 --> 00:08:52,890 evaluate 236 at KSC we will also 55 00:09:01,270 --> 00:08:58,740 evaluate 236 at edwards if we waive off 56 00:09:05,810 --> 00:09:01,280 of KSC will take a hard look at 57 00:09:08,960 --> 00:09:05,820 Saturday's weather at KSC and we will 58 00:09:13,130 --> 00:09:08,970 keep that option open for a Saturday 59 00:09:16,670 --> 00:09:13,140 landing at KSC so the first one we'll 60 00:09:19,100 --> 00:09:16,680 try is a second opportunity at KSC if we 61 00:09:21,980 --> 00:09:19,110 waive off there we'll look at the third 62 00:09:24,410 --> 00:09:21,990 opportunity at KSC and also look at 63 00:09:27,950 --> 00:09:24,420 edwards but we will keep our options 64 00:09:35,170 --> 00:09:27,960 open if it is optimistic for Saturday 65 00:09:37,970 --> 00:09:35,180 landing at KSC will try that also okay 66 00:09:42,550 --> 00:09:37,980 forecaster Saturday they had to pick 67 00:09:48,130 --> 00:09:44,900 yes sir the second or the third 68 00:09:52,580 --> 00:09:48,140 opportunity at Edwards that's to 36 or 69 00:09:55,670 --> 00:09:52,590 237 so if this saturday forecast is 70 00:10:07,320 --> 00:09:55,680 really poor for KSC the chances are you 71 00:10:18,610 --> 00:10:11,019 and I've got some proposed sleep times 72 00:10:20,440 --> 00:10:18,620 for you have a copy if the blue is a the 73 00:10:24,850 --> 00:10:20,450 blue team's not in bed they can be a 74 00:10:28,120 --> 00:10:24,860 hidden that way about now we're 75 00:10:32,260 --> 00:10:28,130 proposing your sleep read sleep at 14 76 00:10:36,940 --> 00:10:32,270 days two hours and 45 minutes proposing 77 00:10:40,810 --> 00:10:36,950 blue to be up at 14 days two hours in a